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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KALRN All Species: 6.67
Human Site: S1891 Identified Species: 16.3
UniProt: O60229 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60229 NP_003938.1 2985 340174 S1891 N K L S L E G S S Y R G S L K
Chimpanzee Pan troglodytes XP_516703 2991 340419 S1897 N K L S L E G S S Y R G S L K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535768 3009 341980 G1914 S K L T L E G G S Y R G S L K
Cat Felis silvestris
Mouse Mus musculus A2CG49 2964 336982 G1863 N K L T L E G G S Y R G S L K
Rat Rattus norvegicus P97924 2959 336568 G1864 S K L T L E G G S Y R G S L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519275 3047 344048 R1881 S K M A L E D R P S S L L V D
Chicken Gallus gallus XP_001234055 3038 345602 G1948 S K L T L E G G S Y R G S L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LUA6 3028 342343 R1877 S K M A L E D R P S T L S V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651960 2263 256958 I1334 E D V I F G N I K E I H H F H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783478 2887 322988 Y1826 K G F S N P G Y I F K Y S I K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 N.A. 97.4 N.A. 97 97 N.A. 61.7 91.8 N.A. 60.9 N.A. 34 N.A. N.A. 21.2
Protein Similarity: 100 98.8 N.A. 98.3 N.A. 98.3 98.3 N.A. 76.4 95.2 N.A. 75.3 N.A. 50.8 N.A. N.A. 39.9
P-Site Identity: 100 100 N.A. 80 N.A. 86.6 80 N.A. 20 80 N.A. 26.6 N.A. 0 N.A. N.A. 26.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 46.6 93.3 N.A. 60 N.A. 6.6 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 20 0 0 0 0 0 0 0 10 % D
% Glu: 10 0 0 0 0 80 0 0 0 10 0 0 0 0 10 % E
% Phe: 0 0 10 0 10 0 0 0 0 10 0 0 0 10 0 % F
% Gly: 0 10 0 0 0 10 70 40 0 0 0 60 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 10 % H
% Ile: 0 0 0 10 0 0 0 10 10 0 10 0 0 10 0 % I
% Lys: 10 80 0 0 0 0 0 0 10 0 10 0 0 0 70 % K
% Leu: 0 0 60 0 80 0 0 0 0 0 0 20 10 60 0 % L
% Met: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 30 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 20 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 20 0 0 60 0 0 0 0 % R
% Ser: 50 0 0 30 0 0 0 20 60 20 10 0 80 0 0 % S
% Thr: 0 0 0 40 0 0 0 0 0 0 10 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 0 0 20 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 60 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _